Laboratory Dry Granulator Market Growth Analysis, Market Dynamics, Key Players and Innovations, Outlook and Forecast 2025-2032
The global laboratory dry
granulator market size was valued at USD 59.4 million in 2024. The market is
projected to grow from USD 63.2 million in 2025 to USD 89.7 million by 2032,
exhibiting a CAGR of 6.1% during the forecast period.
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A laboratory dry granulator is
a specialized piece of equipment used for transforming powders into granules
without liquid binders, primarily serving pharmaceutical, food, and chemical
industries. This technology is critical for small-scale production, R&D,
and formulation development, particularly for moisture-sensitive or
heat-sensitive materials where traditional wet granulation is unsuitable.
The market growth is driven by increasing pharmaceutical R&D
investments, projected to reach USD 260 billion globally by 2025, alongside
stringent regulatory requirements for drug formulation consistency. While North
America currently leads adoption due to strong biopharma sectors, Asia-Pacific
shows the highest growth potential at 7.3% CAGR, fueled by expanding contract
research organizations and generic drug manufacturing in India and China.The
global laboratory dry granulator market is witnessing robust growth driven by
increasing demand for efficient and precise granulation technologies in
pharmaceutical and related industries. As pharmaceutical companies continue to
invest heavily in research and development, the need for advanced dry
granulation equipment that can handle moisture-sensitive and heat-sensitive
compounds has become critical. Laboratory dry granulators offer a reliable, scalable,
and cost-effective solution for producing consistent granules, essential for
developing high-quality drug formulations. Additionally, growing regulatory
emphasis on process consistency and quality control is further accelerating the
adoption of dry granulation methods. With ongoing advancements in automation
and process monitoring, the market is poised for significant expansion across
regions, fueled by the pharmaceutical sector’s continuous innovation and
stringent manufacturing standards.
MARKET DYNAMICS
MARKET DRIVERS
Growing Pharmaceutical
R&D Expenditure to Fuel Market Expansion
The pharmaceutical industry's increasing investment in research
and development is a primary driver for the laboratory dry granulator market.
With global pharmaceutical R&D spending reaching approximately $250 billion
annually, companies are prioritizing formulation development and process
optimization. Dry granulation has become essential for APIs and excipients
sensitive to moisture or heat, with over 35% of new drug candidates requiring
this technology during early-phase development. The ability to produce uniform
granules without solvents makes lab-scale dry granulators indispensable for
formulation scientists working on novel drug delivery systems and stability testing.
National Bureau of Statistics
of China , According to preliminary estimates, China's total expenditure on
research and experimental development (R&D) exceeded 3.6 trillion yuan in
2024, registering 3.6130 trillion yuan, an increase of 8.3 percent over the
previous year
Regulatory Emphasis on
Process Consistency to Stimulate Adoption
Stringent quality requirements from regulatory agencies are
accelerating the adoption of laboratory dry granulators. Current Good
Manufacturing Practice (cGMP) guidelines emphasize robustness in formulation
processes, making granule consistency a critical parameter. Recent data shows
that nearly 42% of pharmaceutical process deviations originate during
granulation, prompting companies to invest in precise lab-scale equipment for
parameter optimization. The technology's ability to maintain powder properties
while improving flow characteristics aligns perfectly with regulatory
expectations for reproducible manufacturing processes from early development
stages.Regulatory bodies such as the FDA (U.S. Food and Drug
Administration), EMA (European Medicines Agency), and other
global authorities are increasingly emphasizing process
consistency and quality control in pharmaceutical
manufacturing.
Expansion of Contract
Research Services to Enhance Market Growth
The rapid growth of pharmaceutical contract research
organizations (CROs) presents significant opportunities for laboratory dry
granulator manufacturers. With the CRO market expanding at approximately 8%
annually, these service providers increasingly require versatile equipment
capable of handling diverse formulations. Laboratory dry granulators offer CROs
the flexibility to work with multiple client projects while maintaining
distinct material characteristics. Recent equipment innovations in small-scale
roller compaction and direct compression systems enable CROs to bridge
formulation development with pilot-scale production more effectively than ever
before.
MARKET RESTRAINTS
High Equipment Costs and
Maintenance to Limit Market Penetration
While offering superior performance, laboratory dry granulators
carry significant acquisition costs that restrain market growth. Premium
laboratory-scale units can cost 3-4 times more than equivalent wet granulation
equipment, with specialized models exceeding $150,000. Maintenance expenses
further compound this challenge – sealed systems for potent compounds require
frequent servicing, while precision rollers demand regular calibration. These
factors create substantial barriers for small research facilities and academic
institutions, limiting adoption primarily to well-funded pharmaceutical
developers and established CROs.
Technical Limitations
with Certain Formulations to Constrain Usage
Technical constraints with specific material properties present
notable challenges for dry granulation adoption. Approximately 28% of
pharmaceutical powders demonstrate poor compactibility without binders,
requiring formulation modifications that complicate early-stage development.
Cohesive powders tend to generate excessive fines during dry granulation, while
some APIs exhibit reduced dissolution rates after compaction. These limitations
force researchers to either accept suboptimal granule properties or invest
additional time in formulation adjustments, slowing the technology's
penetration into certain therapeutic categories.
MARKET CHALLENGES
Skilled Workforce
Shortage to Impede Market Growth
The pharmaceutical industry faces an acute shortage of personnel
trained in dry granulation technologies. Recent workforce analyses indicate
that less than 15% of formulation scientists have hands-on experience with
modern roller compaction systems. This skills gap becomes particularly
problematic when scaling formulations from laboratory to production, where
improper parameter translation can lead to costly process failures. The
complexity of optimizing force, gap width, and feed rate combinations requires
specialized knowledge that remains concentrated in a limited number of
experienced professionals.
MARKET OPPORTUNITIES
Emerging Markets
Expansion to Create New Growth Avenues
Pharmaceutical industry growth in Asia-Pacific regions presents
substantial opportunities for laboratory dry granulator manufacturers.
Countries like India and China are increasing their spending on pharmaceutical
R&D at rates exceeding 12% annually, creating demand for advanced
formulation technologies. Local manufacturers transitioning toward regulated
markets require equipment that can meet international quality standards,
positioning laboratory dry granulators as critical investments for
quality-focused emerging market players.
Continuous Manufacturing
Adoption to Drive Innovation
The industry's shift toward continuous manufacturing creates
compelling opportunities for next-generation laboratory dry granulators. Recent
regulatory endorsements of continuous processes emphasize the need for
equipment that seamlessly transitions from development to production.
Manufacturers integrating process analytical technology (PAT) into laboratory
granulators enable real-time monitoring critical for continuous systems, while
advanced machine learning algorithms help predict scale-up parameters more
accurately than traditional empirical approaches.
LABORATORY
DRY GRANULATOR MARKET TRENDS
Pharmaceutical
R&D Investments to Drive Market Expansion
The laboratory dry granulator market is experiencing robust
growth due to increasing investments in
pharmaceutical research and development, particularly in novel drug
formulation. As pharmaceutical companies and contract research organizations
(CROs) develop more complex drug compounds, the need for efficient small-scale
granulation solutions has intensified. The global pharmaceutical R&D
expenditure surpassed $250 billion in recent years, with a significant portion
allocated to formulation development for solid dosage forms. Dry granulation is
preferred for its ability to handle moisture-sensitive APIs while ensuring
product stability during early-stage testing. Furthermore, regulatory agencies
increasingly demand detailed formulation data before approving large-scale
production, making laboratory-scale equipment indispensable.In
2023, Merck & Co. made a considerable investment in research and
development, spending more than $30 billion.
Other Trends
Automation and Process
Optimization
The integration of advanced automation technologies into
laboratory dry granulators is transforming formulation workflows. Modern
systems now incorporate real-time monitoring sensors and AI-driven process
optimization to improve granule consistency and reduce material waste. In
precision-critical applications such as controlled-release formulations,
automated adjustment of compaction force and feed rates has improved yield by
up to 20% compared to conventional systems. These technological upgrades are
particularly valuable for contract manufacturers handling multiple formulation
projects simultaneously, where equipment flexibility and data reproducibility
are paramount.
Material Science Advancements Open New Possibilities
The market is witnessing growing adoption of laboratory dry
granulators for processing novel excipients and composite materials in
industries beyond pharmaceuticals. In the food sector, manufacturers are
utilizing these systems to develop fortified nutrient granules with precisely
controlled release profiles. Similarly, specialty chemical producers employ dry
granulation to create uniform catalyst carriers for industrial applications.
Equipment manufacturers have responded by developing specialized models with
enhanced corrosion resistance and broader pressure ranges to accommodate diverse
material properties. This cross-industry application trend is expected to
contribute over 30% of new market growth through 2032.
Key Industry Players
Market Leaders Focus on
Innovation and Expansion to Drive Growth
The global Laboratory Dry Granulator market features a
competitive yet fragmented landscape, with established players and regional
manufacturers vying for market share. Fitzpatrick emerges
as a dominant force, leveraging its extensive expertise in particle size
reduction technology and strong foothold in pharmaceutical applications. The
company's emphasis on modular granulator designs and compliance with cGMP
standards has solidified its position in regulated industries.
Hosokawa Micron and Alexanderwerk collectively
hold approximately 28% of the market share as of 2024, according to industry
estimates. Their advantage stems from continuous R&D investments -
Hosokawa's recent launch of the Granulex™ series demonstrates this commitment,
featuring improved compaction control and energy efficiency. Meanwhile, Freund
Corporation has been gaining traction through its
specialized Vector series granulators tailored for pharmaceutical research
applications.
Asia-Pacific manufacturers such as Beijing
LongliTech and Yenchen Machinery are
rapidly expanding their presence, capitalizing on lower production costs and
growing domestic pharmaceutical sectors. These companies have been particularly
successful in supplying affordable laboratory-scale equipment to emerging markets
while gradually improving their technological capabilities to compete globally.
European manufacturers including GERTEIS and L.B.
Bohle maintain strong positions in premium market
segments, differentiating through precision engineering and automation features.
Their focus on ICH Q8 compliance and PAT (Process Analytical Technology)
integration aligns well with the stringent requirements of European
pharmaceutical manufacturers.
Strategic movements in the market include Cadmac's recent
acquisition of complementary technology patents and Prism
Pharma Machinery's expansion into North American markets
through distribution partnerships. These developments indicate an industry-wide
push towards technological differentiation and geographic diversification to capture
growth in the projected $89.7 million market by 2032.
2023, RFI
Ingredients (USA) introduced TruHD dry granulation technology,
aimed at high-speed tablet/capsule manufacturing
2025, Beijing
LongliTech showcased its products at the Maghreb
Pharma Expo 2025 held in Algiers, Algeria, from April 22
to 24, 2025. This participation highlights the company's efforts to expand its
presence in international markets
January 2020,
Hosokawa Alpine AG, a group company of Hosokawa Micron, acquired the Solids
Solutions Group.The acquisition led to the formation of "Hosokawa Solids
Solutions GmbH," enhancing Hosokawa's portfolio in bulk solids handling
List of
Key Laboratory Dry Granulator Companies Profiled
·
Fitzpatrick (U.S.)
·
Hosokawa Micron (Japan)
·
Alexanderwerk (Germany)
·
Freund Corporation (Japan)
·
Beijing LongliTech (China)
·
GERTEIS (Switzerland)
·
L.B. Bohle (Germany)
·
Yenchen Machinery (Taiwan)
·
WelchDry (U.S.)
·
Cadmach (India)
·
Canaan Technology (China)
·
Bepex (Germany)
·
Prism Pharma Machinery (India)
·
KEYUAN (China)
·
KaiChuang Machinery (China)
Segment
Analysis:
By Capacity
Production Capacity
30-200Kg/Hour Segment Leads Due to Optimal Balance Between Efficiency and
Flexibility
The market is segmented based on production capacity into:
·
Production Capacity < 30Kg/Hour
o Primarily
used in small-scale research laboratories and academic settings
·
Production Capacity 30-200Kg/Hour
o Most
popular segment for pharmaceutical formulation development
·
Production Capacity > 200Kg/Hour
o Used in
pilot plants and small-scale manufacturing facilities
By Application
Pharmaceutical Sector Dominates
Market Demand Due to Extensive R&D Activities
The market is segmented based on application into:
·
Pharmacy
o Drug
formulation development
o Solid
dosage form research
·
Chemical Industry
o Specialty
chemicals production
o Catalyst
development
·
Food
o Food
additive research
o Nutritional
supplement development
·
Others
By Type
Roller Compaction Technology
Remains Market Leader for Dry Granulation Processes
The market is segmented based on technology into:
·
Roller Compaction
o Most
widely adopted technology for pharmaceutical applications
·
Slugging
o Traditional
method suitable for smaller batches
·
Advanced Dry Granulation
o Incorporates
automation and process control features
By End User
Research Institutions Show
Significant Adoption for Formulation Development
The market is segmented based on end user into:
·
Pharmaceutical Companies
·
Contract Research Organizations (CROs)
·
Academic and Research Institutions
·
Food Technology Companies
·
Chemical Manufacturers
Regional
Analysis: Laboratory Dry Granulator Market
North America
The North American laboratory dry granulator market is driven by strong
pharmaceutical R&D investments and stringent
regulatory standards set by the FDA. The U.S. pharmaceutical sector alone
invests over $100 billion annually in research, fueling demand for precise
small-scale granulation equipment. While the region leads in technological
adoption, high equipment costs and skilled labor requirements create challenges
for smaller research facilities. Many pharmaceutical and biotech companies
favor compact, automated granulators with real-time monitoring capabilities to
streamline formulation development. Environmental regulations promoting
solvent-free processes further boost dry granulation adoption over wet methods.
Europe
Europe's market thrives on its robust pharmaceutical manufacturing sector and
tight EMA quality standards requiring thorough formulation testing. Germany and
Switzerland, housing major pharmaceutical hubs, account for over 40% of
regional demand. The market sees growing preference for modular
granulators that allow easy integration with other lab
equipment. However, pricing pressure from Asian manufacturers and lengthy
equipment validation processes sometimes hinder adoption. Sustainability
initiatives across the EU are accelerating the shift from wet to dry
granulation, particularly for heat-sensitive biopharmaceutical applications.
Asia-Pacific
The APAC region represents the fastest-growing market, projected to expand at
7.2% CAGR through 2032, driven by China and India's booming pharmaceutical
industries. Cost-effective equipment from domestic manufacturers captures about
60% of local demand, though multinationals still prefer premium imported
machines. While production capacity below 30kg/hour dominates currently,
research facilities are gradually shifting toward mid-range 30-200kg/hour
models. The growing contract research sector and increasing API production are
creating new opportunities across the region. Challenges include inconsistent
power supply in some areas and limited service networks for specialized
equipment.
South America
South America's market shows steady growth led by Brazil's developing
pharmaceutical sector and Argentina's focus on generic drug production.
Economic instability in some countries limits capital expenditure on advanced
equipment, keeping demand concentrated in basic benchtop models. The growing
nutraceutical industry presents new application areas for dry granulators.
Infrastructure limitations and dependence on imported equipment (particularly
from Europe) contribute to longer lead times and higher operational costs.
Recent trade agreements may improve equipment accessibility in the coming
years.
Middle East & Africa
This emerging market is gaining traction as countries like Saudi Arabia and UAE
invest in pharmaceutical manufacturing capabilities. Government initiatives to
build research infrastructure are driving first-time equipment purchases,
though adoption remains modest compared to other regions. The market shows
preference for durable, low-maintenance models suited for harsh climates. While
international pharmaceutical companies establish local facilities, limited
technical expertise in dry granulation techniques slows broader implementation.
Regional collaborations and training programs may help overcome this barrier in
the long term.
Report Scope
This market research report offers a holistic overview of global
and regional markets for the forecast period 2025–2032. It presents accurate
and actionable insights based on a blend of primary and secondary research.
Key Coverage Areas:
·
✅ Market
Overview
o Global
and regional market size (historical & forecast)
o Growth
trends and value/volume projections
·
✅ Segmentation
Analysis
o By
product type or category
o By
application or usage area
o By
end-user industry
o By
distribution channel (if applicable)
·
✅ Regional
Insights
o North
America, Europe, Asia-Pacific, Latin America, Middle East & Africa
o Country-level
data for key markets
·
✅ Competitive
Landscape
o Company
profiles and market share analysis
o Key
strategies: M&A, partnerships, expansions
o Product
portfolio and pricing strategies
·
✅ Technology
& Innovation
o Emerging
technologies and R&D trends
o Automation,
digitalization, sustainability initiatives
o Impact
of AI, IoT, or other disruptors (where applicable)
·
✅ Market
Dynamics
o Key
drivers supporting market growth
o Restraints
and potential risk factors
o Supply
chain trends and challenges
·
✅ Opportunities
& Recommendations
o High-growth
segments
o Investment
hotspots
o Strategic
suggestions for stakeholders
·
✅ Stakeholder
Insights
o Target
audience includes manufacturers, suppliers, distributors, investors, regulators,
and policymakers
FREQUENTLY
ASKED QUESTIONS:
▶ What is the current market size of Global Laboratory Dry
Granulator Market?
The global laboratory dry granulator market was valued at USD
59.4 million in 2024 and is projected to reach USD
89.7 million by 2032, growing at a CAGR of 6.1% during
the forecast period.
▶ Which key companies operate in Global Laboratory Dry Granulator
Market?
Key players include Fitzpatrick,
Hosokawa, Alexanderwerk, Freund Corporation, Beijing LongliTech, GERTEIS, L.B.
Bohle, Yenchen Machinery, WelchDry, and Cadmach, among others.
▶ What are the key growth drivers?
Key growth drivers include rising pharmaceutical R&D
investments, stringent regulatory requirements for drug formulations, and
technological advancements in dry granulation equipment.
▶ Which region dominates the market?
North America currently leads
the market, while Asia-Pacific is
expected to witness the fastest growth due to expanding pharmaceutical
manufacturing capabilities.
▶ What are the emerging trends?
Emerging trends include automation in granulation processes,
integration of Industry 4.0 technologies, and development of compact,
high-efficiency laboratory granulators.
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